Hi Paul, I cleaned my own EGR Valve and got some excellent results in respect of mpg returns. You don't need to remove the fuses to reset the ECU, just disconnect the negative lead from the battery and leave it off for a while. I left mine disconnected overnight but you might not need to leave it that long. have a look at this link to a thread by Matus, it covers the resetting of the ECU in there. Hope this helps.
http://www.lexusowne...showtopic=72447
Bluenose1940, does disconnecting the battery have any effect on anything else ?