Well, I realize I'm three years late to this party but I thought I would chime in - my brother-in-law in Los Angeles, CA, USA has had his Lexus since 1998 or 1999 (bought it brand new) and at this point it has 370,000 miles on it. His excellent mechanic told him there is absolutely nothing wrong with the engine or any major systems that he can see, although the grey paint is worn through on the hood (just cosmetic issues). I can't remember what model he has but I think it may be one of the LS models. For this reason, I am now shopping around for an older LS with low miles on it. My BIL's car has been nothing but reliable for almost two decades. Can't beat the Lexus - and that's coming from someone whose extended family has sworn by Mercedes Benz and Cadillac for a couple of generations!!
