I've had my 2005 reg 400h SE-L for slightly over a month and I've done upwards of 1000 miles in it already. IMHO, the car is clearly a cut above its peers, especially judging by the combination of performance, comfort and economy.
On the motorway, it's more than a match for the above-average crowd. It's fast and never lets you down when you have to complete a tricky overtaking manoeuvre.
In town and country roads, its fuel economy is exceptional (I've never dropped below 30 mpg and the max I've returned is 35 mpg). Even on the motorway, providing you use the cruise control regularly, you'll return an average of around 31 mpg.
The car is extremely roomy and comfortable and quite easy to drive. Also, for a car this size, the handling is quite good.