Here's my take on the subject:
I can get 52-53 MPG on 6th gear at 76 mph acc. to tacho, or 69 acc. to GPS.
Anything above that speed, and the MPG goes into 40s.
This is measured on trips between Lancaster and Bristol, so quite a lengthy drive. (¬200 miles one way)
The most I ever got out of it was 64 mpg, though most of it was driving behind lorries in traffic at 55 mph for good 100 miles.
You can get good mpg out of it, but you do have to resort to cruise control pretty much all the time.
I use it at 30/40 mph in the city, and get between 32 and 40 mpg with cruise control, or about 32/34 mpg manually.
Then 26/28 mpg when my foot's particularly heavy.
I think the trick to getting good mpg out of this car, is like with any diesel: cruise control, good maintenance, especially the fuel filter and EGR. And a good burn of the DPF every month or so (drive at 3000 rpm for 20 minutes).
This is the maintenance I follow and seems to be working for me.
I also manage to avoid the turbo lag by playing with the throttle and clutch rather than just releasing the clutch then accelerating.
i think if I managed to get this MPG out of my '06 now 180k mile IS220D, anybody can.