Horses for courses. I used to be an "enthusiastic" driver (Renault 5GT Turbo, 200SX, Skyline GT-R33, etc.) but I guess age and the ever increasing number of gatso's got to me :P
Jan 2002 decided I wanted effortless refinement, so opted for a 200SE Auto - loved it, the auto box is easily as good as the rental C Class 200 Kompressor Auto I got my hands on, and light years better than a dreadfull Omega 2.6 V6 Auto I had the misfortune of doing 2,500 miles in.
The only reason I changed up to the IS300 5-speed was for the extra shove (even so it's still not hugely fast). So for sheer laziness, I'd go auto, especially as Lexus make such nice auto boxes! For involvement and fun, I'd opt for manual! :)