I can give you some thoughts on the Harrier I bought (basically looks like an RX-300 but has a 2.4L 4/cyl engine instead of the V6).
PROS:
- Theoretically cheaper to run than an RX-300, although depending on the mileage you do that might not be strictly true. No cambelt change and fewer toys to break. I've had mine 6 months and nothing's broken yet, hopefully I'll get a good run out of it with just maintenance items.
- Nice and comfy
- Nice interior
- Aftermarket stereo easy to fit
- Smooth and quiet, very nice to drive around at low speeds
CONS:
- Engine is quite underpowered for the size and weight of the vehicle
- Aftermarket cruise control was expensive to fit, and because of the underpowered engine it will often downshift if climbing a hill with cruise set at motorway speed
- The car is unknown on most car databases that tyre, parts and insurance companies use so doesn't appear on searches
I think if I had to make the decision again I'd be very tempted to go for a 400h or a 450. Hopefully the Harrier will have longer longevity and lower TCO, especially with no risk of a hybrid battery failure, but who knows.