Have you had a look at the BMW or Merc diesels? That's where my money would be going.
I considered a IS220d- having test drove one (and reading the reviews on here), I decided it wasn't for me and replaced my 10 year old IS200 with a Mercedes C220CDI Sport auto (I wanted a auto and diesel).
In summary the IS250 is a good motor, but the IS220d is a bit of a dog. If your heart is really set on a diesel, then look at the offerings from BMW, Mercedes etc.
Edit: Just re-read your post- Out of the cars you have listed, the diesel Accord is a good motor, my brother has a 04 Accord 2.2CDTI for about 4 years now, its been running fine without any problems.