I have had two IS250, one was an SE manual and the one now is fully loaded. Both have been near enough problem free the first one has rear brake caliper sticking (common) and this one has a flicker from the xenon which was fixed FOC. Overall I have been pretty happy, I had a GS300 MK3 after my first IS and that was like driving a luxury jet, just floated on the road. I did deviate away from Lexus and look whats happened I'm back, I do think there a good brand, I know the above post has had some problems, fingers crossed for him problem free now, but I do think the majority of the 250's are solid.